Mouse monoclonal antibodies specific for M and N blood group-related antigens.
نویسندگان
چکیده
منابع مشابه
generation and characterization of mouse hybridomas secreting monoclonal antibodies specific for human igg3
mammalians express several subclasses of the igg molecule. in human being there are four homologous igg subclasses, each of which is structurally unique and has different functions. quantification of igg subclasses is fundamental to clinical assessment and diagnosis of many diseases as such assessments depends on the availability of subclassspecific antibodies (abs), particularly monoclonal ant...
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The CT antigenic determinants have previously been shown to be present on the T200 glycoproteins and other proteins of murine cytotoxic T cell clones but not of T helper clones or nonactivated lymphocytes (1, 2). Two determinants recognized by mAbs CT1 and CT2 are also expressed on thymocytes in a developmentally regulated fashion during fetal thymus ontogeny and are found in a subset of Lyt-2+...
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Background: The unique expression of fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL) has been previously reported. Detecting FMOD in CLL patients using specific anti-FMOD mAbs might provide a promising method in detection, monitoring, and prognosis of CLL. Objectives: In this study, we aimed for producing specific antibodies agains...
متن کاملHighly tumor-reactive, internalizing, mouse monoclonal antibodies to Le(y)-related cell surface antigens.
Two monoclonal antibodies, designated BR64 (IgG1) and BR96 (IgG3), were generated that, according to immunohistology, bind selectively to carcinomas of the colon, breast, ovary, and lung. They have no or very low reactivity with normal human tissues, except for the fact that BR64 strains capillaries in the hearts from certain normal donors and that both monoclonal antibodies stain some epitheli...
متن کاملproduction and characterization of mouse monoclonal antibodies recognizing human pan-igg specific conformational or linear epitopes
background: pan-igg specific monoclonal antibodies (mabs) are essential tools for assessment of humoral immunity, immune deficiency and gammopathy. in this study, four hybridoma clones producing mabs with different specificities for human igg isotypes were established. methods: splenocytes from balb/c mice immunized with fc fractions of human igg were fused with sp2/0 myeloma cells. hybridoma c...
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ژورنال
عنوان ژورنال: Journal of the Japan Society of Blood Transfusion
سال: 1987
ISSN: 1883-8383,0546-1448
DOI: 10.3925/jjtc1958.33.21